February 08, 2010


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eThrombosis

Pulmonary Arterial Hypertension Special Issues and Current Therapeutic Approaches: Part One

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Pulmonary Arterial Hypertension Clinic
Unidad de Investigación Clínica en Medicina S.C., Monterrey, NL, Mexico

The term pulmonary arterial hypertension (PAH) refers to conditions that share common isolated elevations in pulmonary arterial pressure defined as at resting mean pulmonary arterial pressure > 25 mmHg with a normal pulmonary capillary or left atrial pressure (<15 mmHg)1. PAH remains a challenging condition to diagnose and manage. In 1991, estimates from the US Department of Health and Human Services National institutes of Health Registry painted a grim portrait of survival in patients with pulmonary hypertension, establishing primary pulmonary hypertension with one, three, and five year survival rates of 68%, 48% and 34%, respectively 2.

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